Occupational Dermatitis in 194 of 885 Thai Patch-Test Patients
Doctor’s Notes · Life in Motion · Evidence Review
Editorial disclosure: The featured image is an AI-created illustration of a fictional work or daily-life scene. It is not a patient, diagnosis, before-and-after image or Dr. Arsy #003 treatment result.
Reader question: What can this study tell workers, families and occupational-health teams—and what would go beyond the evidence? This review keeps every number attached to its population, denominator, comparator and timepoint.
Study snapshot
| Study element | Reported detail |
|---|---|
| Population | 885 patch-tested patients at Siriraj University Hospital in Thailand; 194 (21.9%) were diagnosed with occupational contact dermatitis. |
| Design | Five-year retrospective review of clinical and patch-test records. |
| Comparator | Allergic and irritant occupational diagnoses, job groups, body sites, allergens and irritants were compared descriptively. |
| Timepoint | Records from 2006 through 2010. |
| Key result | Among 194 occupational cases, 76.3% were classified allergic and 24.2% irritant; hands were involved in 51.5%. Wet work accounted for 35.1% of occupations, and nickel sulfate was the most frequent listed allergen at 33.1%. |
| Funding/conflict context | The PubMed record lists no grant or conflict-of-interest statement. |
What was actually measured?
Among 194 occupational cases, 76.3% were classified allergic and 24.2% irritant; hands were involved in 51.5%. Wet work accounted for 35.1% of occupations, and nickel sulfate was the most frequent listed allergen at 33.1%.
The results describe the mix of cases reaching one patch-test service. The high allergic proportion may reflect the reason people were referred and tested rather than the full occupational burden.
The denominator defines the scope. A patch-test clinic, selected case series, compensation registry, online questionnaire, workplace cohort and general-population survey answer different questions. A percentage from one cannot be silently transferred to the others.
What the result does not prove
Retrospective single-hospital referral data cannot estimate population prevalence. Occupational relevance, exposure classification and documentation may be incomplete or inconsistent.
Association, timing and biological plausibility can strengthen an occupational interpretation, but observational evidence cannot automatically establish individual causation. Referral patterns, reporting practices, task mix, protective equipment, nonwork exposures and access to care may all change an estimate.
A PubMed record is a bibliographic source. PubMed indexing is not NIH endorsement of the authors' conclusions, this interpretation or any product.
Exposure detail matters more than the job label
Workers with the same title can handle different materials for different durations. Useful documentation identifies the exact product or process, the route of contact, glove or PPE material, wetness, friction, heat, dust, splash potential, frequency and how symptoms change away from the task.
A symptom survey can identify a pattern, a clinical examination can refine the differential diagnosis, and patch testing can identify delayed sensitization. None of those steps alone proves that a workplace material caused an individual condition. Clinical relevance still requires a credible exposure and time course.
Questions worth recording
- Which task, product, glove, tool, metal, resin, cleanser, food, plant, dust or surface came before symptoms?
- Where did the change begin, and did it improve on days away or after a process or PPE change?
- How often were hands wet, washed, disinfected, occluded, rubbed, heated or exposed to cold?
- Were labels, ingredient information and safety-data sheets reviewed with occupational health?
- Did the problem affect dexterity, sleep, pace, attendance, work quality or safety?
Prevention comes before cosmetic care
Substitution, closed systems, local exhaust, splash control, safer cleaning methods, training and correctly selected protective equipment address exposure at its source. Gloves are not automatically protective: material, fit, breakthrough time, sweating, reuse and rubber accelerators all matter.
Do not deliberately place workplace products on skin to test a theory. Persistent, recurrent or spreading symptoms, drainage, fever, breathing symptoms, severe pain, rapidly worsening redness or major loss of function warrant professional evaluation.
Primary research and guidance
- Primary research record: PubMed PMID 25675684
- NIOSH: occupational skin exposure
- NIAMS: atopic dermatitis
- American Academy of Dermatology: eczema skin care
Where Dr. Arsy #003 fits
Dr. Arsy #003 is a cosmetic moisturizer for hydration, moisture-barrier support and dry-skin comfort. This study did not test #003. Its findings do not show that #003 treats, cures or prevents eczema, relieves pain or itch, neutralizes workplace chemicals, is appropriate for every person, or provides pediatric or 24-hour efficacy.
Continue the evidence series
- Observed Versus Reported Wet Work in 114 Workers Across 15 Occupations
- Nickel Sensitization in 31,948 North-Eastern Italian Patients
- Combined Allergic-Irritant Diagnoses in 1,000 Occupational Patients
- Preservative Allergy in 141 of 995 Occupational Dermatitis Patients
Evidence note: This educational article separates reported findings from interpretation. It is not a diagnosis, treatment recommendation or workplace-safety determination.